Production of L-amino acids by transamination

Details Production of L-amino acids by transamination Production of L-amino acids by transamination

1983-09-01

1985-05-21

Shapiro, Lionel M.

Chemistry: molecular biology and microbiology

Micro-organism, tissue cell culture or enzyme using process...

Preparing alpha or beta amino acid or substituted amino acid...

435106, 435108, 435113, 435115, C12P 1306, C12P 1304, C12P 1322, C12P 1308, C12P 1312

Patent

active

045186928

ABSTRACT:
A process is described for producing alpha amino acids or derivatives thereof. The process comprises reacting an alpha-keto acid with L-aspartic acid in the presence of transaminase enzyme to produce (1) an alpha amino acid corresponding to said alpha-keto acid and (2) oxaloacetate; and decarboxylating said oxaloacetate.

REFERENCES:
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Tosa et al., in Applied Microbiology, vol. 27, pp. 886-889 (1974).
Umbarger et al., in Annual Review of Microbiology, vol. 47, pp. 533-606 (1978).
Herbert, "Oxalacetic Carboxylase of Micrococcus lysodeikticus", Methods in Enzymology, vol. 1, pp. 753-757.

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