Production of hyaluronic acid

Details Production of hyaluronic acid Production of hyaluronic acid

1995-01-24

1996-10-08

Lilling, Herbert J.

Chemistry: molecular biology and microbiology

Micro-organism, tissue cell culture or enzyme using process...

Preparing compound containing saccharide radical

435 84, 4352521, 435885, 536 551, C12P 1904, C12P 1926, C12N 120

Patent

active

055630510

ABSTRACT:
A process for the production of hyaluronic acid by continuous fermentation of Streptococcus in a chemostat culture gives high yields of high molecular weight hyaluronic acid uncontaminated by toxic impurities. The process is advantageous in that it solves the problem of traditional batch cultures in which degradation enzymes can begin to break down the cell walls of Streptococcus releasing cells contents into the fermenter broth complicating the purification of high molecular hyaluronic acid.

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*English Language Abstract of JP 62-032893 (English Language Abstract only submitted).

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