Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving virus or bacteriophage
Patent
1994-02-07
1996-04-23
Sidberry, Hazel F.
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving virus or bacteriophage
435 71, 435 697, 4351723, 530350, C12P 2106, C12Q 170, C07K 100, G01N 3353
Patent
active
055102387
ABSTRACT:
Antigenic proteins may be expressed in bacteria by use of vectors having inserted therein DNA fragments from an envelope gene. The DNA fragments employed in the example are coding sequences found in the HTLV-I envelope gene. The bacteria used was E. coli. The antigenic proteins are useful in identifying antibodies to the organisms from which the DNA fragments were originally obtained.
REFERENCES:
Maniatis, et al, 1982, Molecular Cloning, Cold Spring Harbor (Chaps. 1, 10-12).
Schupback, et al, 1984, "Serological Analysis of a Subgroup . . . " Science 224: 503-505.
U. Seiki, M., et al., "Human Adult T-Cell Leukemia Virus: Complete Nucleotide Sequence of the Provirus Genome Integrated in Leukemia Cell DNA", PNAS 80:3618-3622 (Jun. 1983).
Z. Lee, T. H., et al., "Human T-Cell Leukemia Virus-Associated Membrane Antigens: Identity of the Major Antigens Recognized After Virus Infection", PNAS 81:3856-3860 (Jun. 1984).
AA. Weis, J. H., et al., "An immunologically active chimaeric protein containing herpes simplex virus type 1 glycoprotein D", Nature 302: 72-74 (3 Mar. 1983).
Lautenberger James A.
Papas Takis S.
Samuel Kenneth
Wong-Staal Flossie
Sidberry Hazel F.
Smith L. F.
The United States of America as represented by the Secretary of
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