Production of human monoclonal antibodies specific for hepatitis

Details Production of human monoclonal antibodies specific for hepatitis Production of human monoclonal antibodies specific for hepatitis

1994-06-14

1996-10-15

Hutzell, Paula K.

Chemistry: molecular biology and microbiology

Spore forming or isolating process

53038815, 5303883, 435 7021, 4241491, C12N 520, C07K 1608

Patent

active

055653545

ABSTRACT:
Monoclonal antibodies effective for the diagnosis and treatment of diseases caused by infection with hepatitis B have been prepared from a cell line obtained by fusing a xenogeneic hybridoma designated SPAZ 4 with blood cells of a patient immunized with hepatitis B vaccine. The invention also provides cocktails of the above monoclonal antibodies specific for different epitopes of hepatitis B surface antigen.

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