Production of homogeneous truncated CNTF

Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Recombinant dna technique included in method of making a...

Patent

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

530350, 530399, 536 235, C12N 1512, C07K 1447, C07K 14475

Patent

active

055938574

ABSTRACT:
There are disclosed neurotrophic factors which are capable of being expressed as polypeptides lacking the microheterogeneity associated with a related native-sequence factor, CNTF. Also disclosed are DNA sequences encoding the neurotrophic factors and methods for expressing and recovering the factors as homogeneous polypeptides.

REFERENCES:
patent: 4997929 (1991-03-01), Collins et al.
patent: 5011914 (1991-04-01), Collins et al.
patent: 5032519 (1991-07-01), Paulson et al.
Sabatini et al. J. Cell Biol 92:1-22 (1982).
Colley et al. J. Biol Chem 264(30):17619-17622 (1989).
Sofer et al. Biotechniques 1(4):198-203 (1983).
Suggs et al 1981. Use of Synthetic oligonucleotides as hybridization Probes. Proc Natl Acad Sci. 78:6613.
Manthrope et al. 1986. Purification of Adult Rat Sciatic Nerve Ciliary Neurotropic Brain Res 367:282.
Lin et al. 1989. Purification, Cloning and Expression of Ciliary Neurotropic Factor. Science 246:1023.
Collins et al. Jan. 11, 1991, Intelligenetics database R06557. New Sciatic Nerve ciliary neuro-.
Collins et al. Dec. 11, 1990. Intelligenetics Database RO6234. Purified sciatic nerve ciliary neuro-.
Collins et al. Jan. 11, 1991 Intelligenetics Database Q05801. New Sciatic nerve ciliary neurotropic.
Collins et al. Dec. 11, 1990. Intelligenetics Database Q05528. Purified Sciatic Nerve ciliary neurotropic.
Adler and Varon, Brain Res. (1980) 188:437-448.
Landa et al., Dev. Biol. (1980) 74:401-408.
Manthorpe et al., J. Neurochem. (1980) 34(1):69-75.
Manthorpe et al., J. Neurochem. (1982) 38:415-421.
Barbin et al., J. Neurochem. (1984) 43(5):1468-1478.
Manthorpe et al., Brain Res. (1986) 367:282-286.
Stockli et al., Nature (1989) 342:920-923.

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Production of homogeneous truncated CNTF does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Production of homogeneous truncated CNTF, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Production of homogeneous truncated CNTF will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-1387420

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.