Production of heterologous proteins in filamentous fungi

Details Production of heterologous proteins in filamentous fungi Production of heterologous proteins in filamentous fungi

1995-06-06

1997-10-07

Chambers, Jasemine C.

Chemistry: molecular biology and microbiology

Micro-organism, tissue cell culture or enzyme using process...

Recombinant dna technique included in method of making a...

4353201, 43525411, 4351723, 536 241, C12N 1509, C12N 1563, C12N 115, C07H 2104

Patent

active

056747071

ABSTRACT:
Expression of proteins in filamentous fungal hosts is achieved in the presence of glucose using promoter variants in which creA binding sites are functionally disrupted.

REFERENCES:
Hintz et al. (1993) Bio/Technology 11:815-818.
P. Kulmburg et al. "Specific binding sites in the alcR . . ." Molecular Microbiology (1993) 7(6), pp. 847-857.
D.W. Griggs et al. "Regulated expression of the GAL4 . . ." Proc. Natl Acad. Sci. USA vol. 88, Oct. 1991, 8597-8601.
Ward, M. "Aspergilus nidulans and other filamentous . . ." Modern Microbial Genetics, 1991, Wiley-Liss, Inc., pp. 455-495.
Gwynne, D.I. et al. "Genetically engineered secretion . . ." Biotechnology, 5(1987), pp. 713-719.
Buxton, et al. "Cloning of the structural gene . . ." Mol Gen Genet, 190 (1983), pp. 403-405.
Royer, J.C. et al. "Analysis of a high frequency transformation . . ." Mol Gen Genet, 225 (1991), pp. 168-176.
R. Lockington et a. "Regulation of alcR, the positive . . ." Molecular Microbiology (1987) 1(3), pp. 275-181.
D.I. Gwynne et al. "Comparison of the cis-acting control regions . . ." Gene 31 (1987), Elservier Science Publishers (Biochemical Div.), pp. 205-216.
B. Belenbok et al. "Regulation of Genes Involved . . ." Proceedings of the EMBO, Helsinki, 1989, pp. 73-83.
P. Kulmburg et al. "Specific binding sites for the activator. . ." The Journal of Biological Chemistry, vol. 267, No. 29, 1992 Oct. 15 issue, pp.21146-21153.
Molecular Biology of Filamentous Fungi, Proceedings of the EMBO-Workshop, Berlin, Aug. 24-29, 1991, edited by U. Stahl and P. Tudzynski.
J.O. Nehlin et al. "Control of yeast GAL genes . . ." The EMBO Journal, vol. 10, No. 11, 1991, pp. 3373-3377.
D.J. Gwynne et al. "Current use and continued development of an expression system . . ." Proceedings of the EMBO - Helsinki, 1989, pp. 129-136.
H. V. Baker. "GCRI of Saccharomyces cerevisiae encodes a DNA . . ." Proc. Natl. Acad. of Sciences, USA, vol. 88 Nov. 1991, pp. 9443-9447.

Affiliated with

Also associated with

Rating

Production of heterologous proteins in filamentous fungi does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Production of heterologous proteins in filamentous fungi, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Production of heterologous proteins in filamentous fungi will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-2356202