Production of herpes simplex viral porteins

Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Recombinant dna technique included in method of making a...

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435 70, 435 71, 4351721, 4351723, 4352401, 4352402, 435243, 4352523, 435255, 435256, 435320, 43525233, 536 27, 935 12, 935 28, 935 29, 935 52, 935 66, 935 67, 935 70, 935 72, 935 73, C12P 2100, C12P 2102, C12P 2104, C12N 1500, C12N 500, C12N 100, C12N 120, C12N 116, C12N 118, C07H 2104

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048913154

ABSTRACT:
Methods and compositions are provided for the cloning and expression of Herpes Simplex Virus (HSV type 1 or type 2) glycoprotein (gD) gene in single-cell host organisms. Also described are methods for culturing these novel single-cell organisms to produce HSV-gene products. The HSV gD-related polypeptides produced by the recombinant DNA techniques described herein may be formulated for use as immunogens in vaccines to protect against HSV-1 and HSV-2 infections.

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