Production of galactosyltransferase

Chemistry: molecular biology and microbiology – Enzyme – proenzyme; compositions thereof; process for... – Transferase other than ribonuclease

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435325, 435355, 435 704, 4353201, 536 232, C12N 1509, C12N 1554, C12N 510

Patent

active

058561595

ABSTRACT:
A gene expression system for producing galactosyltransferase comprises an NSO cell recombinantly modified with a polynucleotide encoding galactosyltransferase or a portion thereof which catalyzes the reaction:

REFERENCES:
patent: 5627033 (1997-05-01), Smith et al.
patent: 5674834 (1997-10-01), Theofan et al.
C.R. Bebbington et al., "High-Level Expression of a Recombinant Antibody From Myeloma Cells Using a Glutamine Synthetase Gene as an Amplifiable Selectable Marker", Biotechnology 10(2): 169-175, Feb. 92.
H. Narimatsu et al., "Cloning and Sequencing of cDNA of Bovine N-Acetylglucosamine (.beta.1-4) Galactosyltransferase", Proc. Natl. Acad. Sci. 83:4720-4724.
S.S. Apte et al., "The Gene Structure of Tissue Inhibitor of Metalloproteinases (TIMP)-3 and Its Inhibitory Activities Define the Distinct TIMP Gene Family", J. Biol. Chem. 270(24): 14313-14318, Jun. 95.

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