Production of furanones

Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...

Reexamination Certificate

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C514S473000

Reexamination Certificate

active

07064220

ABSTRACT:
The present invention relates to the side chain functionalization of fimbrolides (halogenated 3-alkyl-5-methylene-2(5H)-furanones) and their synthetic analogues, that yields fimbrolides substituted with a halogen, an oxygen or a nitrogen functionality in the alkyl chain, especially fimbrolide alcohols, carboxylate and sulfinate and sulfonate esters, ethers, aldehydes, ketones, acids, amides, nitro derivatives, hydrophobic, hydrophilic and fluorophilic alkyl derivatives and a polymers.

REFERENCES:
patent: 6635692 (2003-10-01), Christie et al.
patent: 2004/0072898 (2004-04-01), Kjelleberg et al.
patent: WO 96/29392 (1992-09-01), None
Kjelleberg et al. “Methods for microbial . . . ” CA 126:4540 (1996).
Manny et al. “Reinvestigation of . . . ” CA 128:34643 (1997).
Kotsuki et al. “Efficient synthesis . . . ” Chem Lett p. 1007-1008 (1983).
Cueto et al. “New acetyl derivatives . . . ” J. Nat. Prod. v. 60 p. 279-281 (1997).
Manny et al. “Reinvestigation . . . ” Tetrahedron v. 53 p. 15813-15826 (1997).

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