Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving nucleic acid
Reexamination Certificate
2005-09-20
2005-09-20
Lacourciere, Karen A. (Department: 1635)
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving nucleic acid
C435S325000, C435S375000, C536S024500
Reexamination Certificate
active
06946246
ABSTRACT:
The present invention provides for a method of culturing cells and inducing the expression of at least one gene in the cell culture. The method provides for contacting the cell with a transcription factor decoy oligonucleotide sequence directed against a nucleotide sequence encoding a shear stress response element.
REFERENCES:
patent: 5153132 (1992-10-01), Goodwin et al.
patent: 5155034 (1992-10-01), Wolf et al.
patent: 5496722 (1996-03-01), Goodwin et al.
patent: WO 95/11687 (1994-10-01), None
Antisense '97: A roundtable on the state of the industry. Nature Biotechnol. 15 (1997): 519-524.
Gewirtz et al. Facilitating oligonucleotide delivery: Helping antisense deliver on its promise. Proc. Natl. Acad. Sci. USA 93 (1996): 3161-3163.
Jen et al. Suppression of gene expression by targeted disruption of messenger RNA: Available options and current strategies. Stem Cells 18 (2000): 307-319.
Khachigian et al. Nuclear factor -kB interacts functionally with the platelet-derived growth factor B-chain shear-stress response element in vascular endothelial cells exposed to fluid shear stress. J. Clinical Invest. (Aug., 1995) 96 (2): 1169-1175.
Rojanasakul, Y. Antisense oligonucleotide therapeutics: Drug delivery and targeting. Adv. Drug Delivery Rev. 18(1996): 115-131.
Stull et al. Antigene, ribozyme, and aptamer nucleic acid drugs: Progress and prospects. Pharm. Res. 12(1995): 465-483.
J Ando et al., Jpn Heart J.,“Flow-dependent Regulation of Gene Expression in Vascular Endothelial Cells,” 1996-37:19-32.
Goodwin TJ, et al., J cell Biochem 51:301-311, 1993.
Jessup JM, et al., J Cell Biochem 52:290-300, 1993.
Spaulding GF, et al. J. Cell Biochem 51:249-251, 1993.
DeLuca HF., et al., Ann NY Acad Sci 669:59-68, 1992.
Hammond T. G. et al., Kidney Int 42:997-1005, 1992.
Hammond T. G., et al., Cytometry 14:411-420, 1993.
Wolf D. A. and R. P. Schwarz (1991) NASA Technical Paper 3143.
Moestrup, et al., J. Biol. Chem. B273 (9); 5235-5242 (1998).
Goodwin Thomas John
Hammond Timothy Grant
Kaysen James Howard
Lacourciere Karen A.
Ro Theodore U.
The United States of America as represented by the Administrator
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