Production of cyclopentenylheptanoic acid derivatives

Details Production of cyclopentenylheptanoic acid derivatives Production of cyclopentenylheptanoic acid derivatives

1986-02-24

1989-07-18

Gerstl, Robert

Organic compounds -- part of the class 532-570 series

Organic compounds

Silicon containing

560121, 562503, C07C17700

Patent

active

048495352

ABSTRACT:
Cyclopentenylheptanoic acid derivatives having the formula: ##STR1## wherein R is hydrogen or C.sub.1 to C.sub.4 alkyl and --(A)-- is: ##STR2## wherein M is hydrogen or triorganosilyl group, are prepared by reacting a compound having the formula: ##STR3## ps wherein X is halogen, with a compound having the formula: The derivatives belong to the pharmacologically-active class of compounds called "prostaglandins".

REFERENCES:
patent: 3922299 (1975-11-01), Heck
patent: 4658055 (1987-04-01), Onuki
Heck, Accts of Chem. Res. 12 147 (1979).
Novak, Chem. Ber., 113, 2939 (1980).

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