Production of cyanide hydratase

Details Production of cyanide hydratase Production of cyanide hydratase

1992-05-20

1993-06-15

Patterson, Jr., Charles L.

Chemistry: molecular biology and microbiology

Enzyme , proenzyme; compositions thereof; process for...

Lyase

435245, 4352625, 435813, 435821, 210606, 210632, C12N 988, C02F 334

Patent

active

052197506

ABSTRACT:
A process for the production of the enzyme cyanide hydratase which comprises continuously cultivating a microorganism strain under specified conditions of temperature, pH and dilution rate whilst continuously supplying cyanide ions and/or hydrogen cyanide and/or compounds which generate cyanide ions and/or hydrogen cyanide under fermentation conditions to the culture. A method for the treatment of a cyanide-containing material to degrade the cyanide therein which uses cyanide hydratase produced by the process of the invention is also claimed. Preferably the microorganism is a Fusarium strain, in particular Fusarium lateritium Naas CM1 300533 deposited at The Commonwealth Mycological Institute, Kew, Richmond Surrey, England under the terms of the Budapest Treaty.

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