Production of complementary DNA representing hepatitis A viral s

Details Production of complementary DNA representing hepatitis A viral s Production of complementary DNA representing hepatitis A viral s

1995-06-06

1998-12-15

Ketter, James

Chemistry: molecular biology and microbiology

Spore forming or isolating process

4352351, 435236, 536 231, C12N 516

Patent

active

058495622

ABSTRACT:
Methods for producing HAV cDNA, products thereof, and uses thereof, are described. HAV cDNA is produced, for example, by reverse transcribing HAV RNA and subsequently inserting the HAV cDNA into bacterial plasmids by genetic-engineering techniques. Transformed bacteria are then cloned and cultured to produce replicated chimeric plasmids containing the HAV cDNA. Such HAV cDNA is useful in assaying for the presence of HAV and in the production of HAV antigen and in the production of antibodies against HAV.

REFERENCES:
patent: 4894228 (1990-01-01), Purcell et al.
patent: 5478746 (1995-12-01), Cohen et al.
Cohen, J. et al. 1989 J. of Virology pp. 5364-5370.
Emerson, S. et al. 1989 Vaccines 89 Modern Approaches to New Vaccines including Prevention of AIDS Eds Lerner, Ginsbers, Chanock, Brown. Cold Spring Harbor pp. 427-430.
Cohen et al., (1987) J. Virol., 63: 5364-5370.
Cohen et al., (1987) J. Virol., 61: 3035-3039.
Cohen et al., (1987) Proc. Natl. Acad. Sci. U.S.A., 84: 2497-2501.
Emerson et al., (1989) "Identification of the Hepatitis A Virus Genes Involved in Adaption to Tissue Culture Growth and Attenuation" in Vaccines 89, Cold Spring Harbor Laboratory, pp. 427-430.
Emerson et al., (1991) J. Virol., 65: 4882-4886.

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