Production of clostridium acetobutylicum mutants of high butanol

Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Preparing oxygen-containing organic compound

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435160, 435253, 435842, C12P 728, C12P 716, C12N 120, C12R 1145

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active

047570105

ABSTRACT:
The Clostridium acetobutylicum mutant IFP 904 (ATCC 39058) is obtained by spreading a culture of a strain of Clostridium acetobutylicum at the surface of a solid culture medium containing n-butanol at a specified concentration, growing the strain in the presence of a mutagenic agent and recovering a strain of increased resistance to n-butanol. The resultant mutant can be used to produce a mixture of butanol and acetone of increased concentration.

REFERENCES:
patent: 4352880 (1982-10-01), Awerbuch
Demain, Genetics of Industrial Microorganisms, vol. I, Elsevier Publishing Co., N.Y., (1973) pp. 21-23.
The Microbial World, 4th Ed., 1976, Prentice-Hall International, Inc., London, pp. 407 and 409.

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