Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues – Hormones – e.g. – prolactin – thymosin – growth factors – etc.
Patent
1990-10-09
1993-08-10
Wityshyn, Michael G.
Chemistry: natural resins or derivatives; peptides or proteins;
Proteins, i.e., more than 100 amino acid residues
Hormones, e.g., prolactin, thymosin, growth factors, etc.
530402, 530404, 530412, 530417, 530418, 530419, 530422, 536 2351, 536 235, 435 691, 435 711, 4351723, 435849, 935 13, C07K 314, C12N 1500
Patent
active
052350436
ABSTRACT:
This invention describes processes for producing mature human members of the NGF/BDNF family of neurotrophic proteins that are fully biologically active. In addition, the gene encoding human BDNF and processes for obtaining the same are disclosed.
A previously-unreported member of the NGF/BDNF family of neurotrophic proteins, NGF-3, has been identified and a portion of the gene encoding for the NGF-3 has been described. Processes for identifying additional previously unreported members of the NGF/BDNF family are also described.
REFERENCES:
patent: 4511502 (1985-04-01), Builder
patent: 4511503 (1985-04-01), Olson
patent: 4512922 (1985-04-01), Jones
patent: 4599197 (1986-07-01), Wetzel
patent: 4766205 (1988-09-01), Ghosh-Dastidar
patent: 4929700 (1990-04-01), Halenbeck
Edington, Bio/Technology, 10:376, Apr. 1992.
Bektesh Susan
Collins Frank
Kohno Tadahiko
Lile Jack
Mohamed Abdel A.
Synergen, Inc.
Wityshyn Michael G.
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