Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues – Chemical modification or the reaction product thereof – e.g.,...
Patent
1997-08-27
1999-11-16
Allen, Marianne P.
Chemistry: natural resins or derivatives; peptides or proteins;
Proteins, i.e., more than 100 amino acid residues
Chemical modification or the reaction product thereof, e.g.,...
530412, 530402, C07K 114
Patent
active
059860707
ABSTRACT:
This invention describes processes for producing mature human members of the NGF/BDNF family of neurotrophic proteins that are fully biologically active. In addition, the gene encoding human BDNF and human BDNF are disclosed. A previously-unreported member of the NGF/BDNF family of neurotrophic proteins, NGF-3, has been identified and a portion of the gene encoding for the NGF-3 has been described.
REFERENCES:
patent: 4421685 (1983-12-01), Chance et al.
patent: 4451396 (1984-05-01), DiMarchi
patent: 4511502 (1985-04-01), Builder
patent: 4511503 (1985-04-01), Olson et al.
patent: 4512922 (1985-04-01), Jones
patent: 4518526 (1985-05-01), Olson
patent: 4599197 (1986-07-01), Wetzel
patent: 4620948 (1986-11-01), Builder et al.
patent: 4766205 (1988-08-01), Ghosh-Dastidar
patent: 4873312 (1989-10-01), Arakawa
patent: 4923967 (1990-05-01), Bobbit et al.
patent: 4929700 (1990-05-01), Halenbeck
patent: 5169762 (1992-12-01), Gray
patent: 5169764 (1992-12-01), Shooter
patent: 5180820 (1993-01-01), Barde et al.
patent: 5210185 (1993-05-01), Della Valle
patent: 5235043 (1993-08-01), Collins et al.
Sarmientos et al. (1989) Biotechnology 7:495.
Translation of Protein Molecules, Iwanami Shoten Co., pp. 99-129 (1985), Chapter 7.
Jaenicke et al., "Folding Proteins" in Protein Structure--A Practical Approach, Creighton, TE. ed., Oxford, pp. 191-223 (1990).
Scopes, Protein Purification--Principles and Practice, Springer-Verlag, NY, Table of Contents, pp. 33-35, 45-54, 93-99, 111,113, 199,208, 285,290 (1987).
Winkler, M.E. et al. J. Biol. Chem. 261:13838-43 (1986).
Van Snick, J. et al. Eur. J. Immunol. 18:193-197 (1988).
Hu and Neet (1988) Gene 70:57-65.
Kelley and Winkler (1990) Genetic Engineering 12:1-19, Ed. J.K. Setlow, Plenum Press, NY and London.
Leibrock et al. Nature 341:149-152 (1989).
Jones et al. Proc. Natl Acad Sci USA 87:8060-8064 (1990).
Hofer et al Nature 331: 261-262 (1988).
Barde et al. EMBO J. 1: 549-53 (1982).
Ernfors et al. Proc. Natl Acad Sci 87: 5454-5458 (1990).
Hufer et al EMBO J. 9:2459-2464 (1990).
Maisonpierre et al Genomics 10: 558-568 (1991).
Cleland et al. (1992) J. Biol. Chem. 267:13327.
Dicou et al. (1989) J. Neurosci. Res. 22:13.
Edwards et al. (1988) Molec. and Cell Biol. 8:2456.
Edwards et al. (1986) Nature 319:784.
Gonzalez and Damodaran (1990) J. Agric. Food Chem. 38:149.
Iwai et al. (1986) Chem. Pharm. Bull. 34:4724.
Knusel et al. (1991) PNAS 88:961.
Kohno (1990) Methods Enzymol. 185:187.
Leibrock et al. (1989) Nature 341:149.
Light (1985) Biotechniques 3:298.
Maisonpierre et al. (1990) Science 247:1446.
Ullrich et al. (1983) Nature 303:821.
Becktesh Susan
Collins Frank D.
Kohno Tadahiko
Lile Jack
Mismer, deceased Drizislav
Allen Marianne P.
Amgen Inc.
LandOfFree
Production of biologically active NGF proteins does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Production of biologically active NGF proteins, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Production of biologically active NGF proteins will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-1326327