Production of autocrine growth factors

Details Production of autocrine growth factors Production of autocrine growth factors

1987-06-24

1992-08-04

Stone, Jacqueline

Chemistry: molecular biology and microbiology

Micro-organism, tissue cell culture or enzyme using process...

Using tissue cell culture to make a protein or polypeptide

4352402, 4352403, 43524031, 530399, C12P 2100, C12N 506, C12N 502

Patent

active

051358565

ABSTRACT:
A method of producing autocrine growth factors from kidney epithelial cells by lowering the extracellular sodium concentration. The invention also concerns new growth factors, a method of producing the new growth factors, and the medium used to produce these new growth factors.

REFERENCES:
Walsh-Reitz et al., 1986 Proc. Natl. Acad. Sci. USA 83, 4764-4768.
Holley et al., 1980 Proc. Natl. Acad. Sci. USA 77, 5989-5992.
Moolenaar et al., 1981 Cell 23, 789-798.
Sporn et al., 1985 Nature 313, 745-747.
Mordan et al., 1984 Am. J. Physiol. 246, C351-C354.
Walsh-Reitz et al., 1984 Am. J. Physiol. 247. C321-C326.
Toback et al., 1984 Am. J. Physiol. 247, C14-C19.

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