Production of antisera specific to major histocompatibility comp

Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues – Blood proteins or globulins – e.g. – proteoglycans – platelet...

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4241981, 435349, 5303896, C07K 1628, C12N 1585, C12N 1563

Patent

active

060751258

ABSTRACT:
Host cells transfected with a recombinant DNA molecule which includes a DNA sequence inserted therein encoding a heterologous chicken BFIV MHC class I protein are disclosed. The transfected cells express the heterologous BFIV protein and may be used as an immunogen to produce chicken MHC class I (BFIV) specific antisera. The antisera so produced may then be used to determine the BF haplotype of any chicken.

REFERENCES:
Fulton et al. Poultry Sciences 75:10, Jul. 1996.
Goodenow et al. Nature 300:231, 1992.
Bradley et al. Immunology 57: 443, 1986.
DiSanto et al. J. Immunological Methods:141:123, 1991.
Fulton et al. Poultry Science 71:10, 1992.
Hunt et al. Immunogenetics 40: 370, 1994.
Thacker et al. J. Virology 69:6439, 1995.
Fulton et al. Eur. J. Immunol. 24: 2069, Jul. 1996.
Mathias et al. J. Immunology 144: 607, 1990.

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