Production of antibody toward asbestos and immunoassay therewith

Details Production of antibody toward asbestos and immunoassay therewith Production of antibody toward asbestos and immunoassay therewith

1979-08-27

1981-02-03

Fagelson, Anna P.

Drug, bio-affecting and body treating compositions

Radionuclide or intended radionuclide containing; adjuvant...

Molecular bilayer structure

23230B, 250302, 424 1, 424 7, 424 12, G01N 3354, G01N 3358, G01N 3384

Patent

active

042488540

ABSTRACT:
The invention provides a reaction product of chrysotile asbestos with an antigenic serum protein, preferably albumin, that has particular utility as an antigen in producing antibody to asbestos. The reaction product of asbestos with an antigenic serum protein also can be used in a method for producing an antibody toward asbestos by immunizing a laboratory animal with the reaction product, of asbestos and a serum protein, allowing it to remain in the blood of the animal for a sufficient period of time and thereafter recovering antibody globulins from the laboratory animal.

REFERENCES:
Lukens et al., Biol. Abs., vol. 64, 1977, Ab. No. 5278.
Lukens, Biol. Abs., vol. 67, 1979, Ab. No. 51441.
Kagan, Chem. Abs., vol. 87, 1977, Ab. No. 87: 79383e.
Williams, Methods in Immunol & Immunochem., Acd. Press, N.Y., vol. V, 1976, p. 424-437.

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