Production of angiogenic factor by cell culture

Details Production of angiogenic factor by cell culture Production of angiogenic factor by cell culture

1980-03-03

1981-05-19

Tanenholtz, Alvin E.

Chemistry: molecular biology and microbiology

Micro-organism, tissue cell culture or enzyme using process...

435240, 435948, C12P 100

Patent

active

042686296

ABSTRACT:
Process for the production of human angiogenic factor in vitro comprising growing the human diploid cell line IMR-90 on support surface in nutrient culture medium at about 35.degree.-38.degree. C. for a sufficient time to elaborate angiogenic factor and recovering the resulting angiogenic factor from the cells or cell product.

REFERENCES:
Adv. Canc. Res. 19, 331-358 (1974).
Arch. Dermatol, 111, 321-327 (1975).
J. Invest. Dermatol. 61, 130-141 (1973).
Microvas. Res. 10, 396-413 (1975).
Proc. Natl. Acad. Sci. USA 75, (2) 847-851 (1978).
Nichols, Science, vol. 196, pp. 60-63 (1977).

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