Production of angiogenic factor by cell culture

Details Production of angiogenic factor by cell culture Production of angiogenic factor by cell culture

1980-03-03

1981-06-16

Tanenholtz, Alvin E.

Chemistry: molecular biology and microbiology

Micro-organism, tissue cell culture or enzyme using process...

435240, 435948, C12P 100

Patent

active

042738717

ABSTRACT:
Process for the production of human angiogenic factor in vitro comprising growing cells of human foreskin fibroblast cell line on support surface in nutrient culture medium at about 35.degree.-38.degree. C. for a sufficient time to elaborate angiogenic factor and recovering the resulting angiogenic factor from the cells or cell product.

REFERENCES:
Adv. Cancer Res. 19, 331-358 (1974).
Arch Dermatol. 111, 321-327 (1975).
J. Invest. Dermatol, 61, 130-141 (1973).
Microvas. Res. 10, 396-413 (1975).
Proc. Natl. Acad. Sci. USA 75, (2) 841-851 (1978).
Cancer Res. 36, 110-114 (1978).
Kruse et al., Tissue Culture Methods and Applications pp. 593-599 (1973).

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