Chemistry: molecular biology and microbiology – Enzyme – proenzyme; compositions thereof; process for... – Hydrolase
Patent
1991-08-02
1993-12-28
Naff, David M.
Chemistry: molecular biology and microbiology
Enzyme , proenzyme; compositions thereof; process for...
Hydrolase
435243, 43525232, 4352548, 4352533, C12N 916, C12N 100, C12N 120
Patent
active
052738973
ABSTRACT:
A process for producing an esterase by cultivating an esterase-producing microorganism is disclosed. The cultivation is carried out in a medium to which has been added an ester of sorbitan or polyoxyethylene sorbitan and a substituted or unsubstituted fatty acid having 12 to 18 carbon atoms along with an amino acid which has the formula: ##STR1## wherein R.sup.1 is hydrogen or a lower alkyl group which may be substituted with a substituent selected from the group consisting of hydroxy, carboxy, amino, guanidino, carbamoyl, mercapto, methylthio, phenyl, hydroxyphenyl, imidazolyl and indolyl, and R.sup.2 is hydrogen, or R.sup.1 and R.sup.2 are combined to form trimethylene.
REFERENCES:
patent: 4803275 (1989-02-01), Kanamaru et al.
patent: 5013757 (1991-05-01), Kanamaru et al.
patent: 5110722 (1992-05-01), Brockbank et al.
Archiv. Biochem. Biophys., vol. 160, pp. 504-513 (1974).
J. Biochem., vol. 95, pp. 1047-1054 (1984).
Sato Motoyoshi
Shibatani Takeji
Takahashi Kouhei
Yanagiya Kouji
Meller Michael V.
Naff David M.
Tanabe Seiyaku Co. Ltd.
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