Production of amoxicillin

Details Production of amoxicillin Production of amoxicillin

1975-03-17

1976-09-14

Schwartz, Gerald A.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

C07D49968

Patent

active

039806375

ABSTRACT:
In the production of amoxicillin by acylation of silylated 6-aminopenicillanic acid with the appropriate acid chloride hydrochloride the efficiency of the process and the purity of the product are increased by a new recovery process consisting of isolation from the acylation reaction mixture of solid amoxicillin hydrochloride which is then easily converted to amoxicillin trihydrate.

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