Production of amino acids using coupled enzyme systems

Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Preparing alpha or beta amino acid or substituted amino acid...

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435107, 435108, 435109, 435110, 435113, 435114, 435115, 435116, 435175, C12P 1304, C12P 1322

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active

048807389

ABSTRACT:
A biocatalytic method for producing a desired amino acid is disclosed. The method involves contacting a 2-ketoacid corresponding to the desired amino acid with lactic acid, aspartic acid and ammonia, or salts thereof, in the presence of:

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patent: 4416992 (1983-11-01), Arera et al.
patent: 4518692 (1985-05-01), Rozzell
Allen, "Lactate-Oxaloacetate Transhydrogenase from Veillonella Alcalescens", Methods in Enzymology, vol. 89, 367-376, 1982.
Rozzell et al., "Combining Enzymatic and Chemical Steps in the Synthesis of Biochemically Valuable Compounds: Isotopically Chiral Methyl Acetate", J. Org. Chem., vol. 48, 1190-1193, 1983.

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