Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Preparing alpha or beta amino acid or substituted amino acid...
Patent
1986-06-13
1989-11-14
Warren, Charles F.
Chemistry: molecular biology and microbiology
Micro-organism, tissue cell culture or enzyme using process...
Preparing alpha or beta amino acid or substituted amino acid...
435107, 435108, 435109, 435110, 435113, 435114, 435115, 435116, 435175, C12P 1304, C12P 1322
Patent
active
048807389
ABSTRACT:
A biocatalytic method for producing a desired amino acid is disclosed. The method involves contacting a 2-ketoacid corresponding to the desired amino acid with lactic acid, aspartic acid and ammonia, or salts thereof, in the presence of:
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Allen, "Lactate-Oxaloacetate Transhydrogenase from Veillonella Alcalescens", Methods in Enzymology, vol. 89, 367-376, 1982.
Rozzell et al., "Combining Enzymatic and Chemical Steps in the Synthesis of Biochemically Valuable Compounds: Isotopically Chiral Methyl Acetate", J. Org. Chem., vol. 48, 1190-1193, 1983.
Berstein David L.
Eisen Bruce M.
Genetics Institute Inc.
Knox Gail
Warren Charles F.
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