Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Recombinant dna technique included in method of making a...
Patent
1998-02-13
2000-10-03
Smith, Lynette R. F.
Chemistry: molecular biology and microbiology
Micro-organism, tissue cell culture or enzyme using process...
Recombinant dna technique included in method of making a...
435 697, 435 698, 435 701, 536 231, 536 236, 536 241, 800320, 8003202, C12P 2106, C12P 2104, C07H 2102, A01H 500
Patent
active
061271454
ABSTRACT:
A method for producing .alpha..sub.1 -antitrypsin (AAT) in plant cells is disclosed. Monocot plant cells transformed with an AAT coding sequence are cultivated under conditions efficient for protein expression and secretion. Also disclosed are a codon-optimized AAT coding sequence that is efficiently translated in plant cell culture and a novel AAT protein having the glycosylation pattern characteristic of plant cells and suitable for therapeutic use in humans.
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Rodriguez Raymond L.
Sutliff Thomas D.
Applied Phytologics, Inc.
Dehlinger Peter J.
Petithory Joanne R.
Smith Lynette R. F.
Zaghmout Ousama M-Faiz
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