Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues – Separation or purification
Reexamination Certificate
2011-05-10
2011-05-10
Kim, Alexander D (Department: 1656)
Chemistry: natural resins or derivatives; peptides or proteins;
Proteins, i.e., more than 100 amino acid residues
Separation or purification
C530S350000
Reexamination Certificate
active
07939643
ABSTRACT:
This invention relates to a process for the production of a von Willebrand factor preparation, hydroxylapatite being used as a chromatography medium.
REFERENCES:
patent: 4341764 (1982-07-01), Wallace et al.
patent: 4774323 (1988-09-01), Newman et al.
patent: 4789733 (1988-12-01), Winkelman et al.
patent: 5128245 (1992-07-01), Greenberg et al.
patent: 5408039 (1995-04-01), Burnouf-Radosevich et al.
patent: 5441635 (1995-08-01), Ichitsuka et al.
patent: 5710254 (1998-01-01), Newman et al.
patent: 6465624 (2002-10-01), Fischer et al.
patent: 2007/0135619 (2007-06-01), Kretschmar et al.
patent: 2007/0203330 (2007-08-01), Kretschmar et al.
Mumby et al., Interactions of Thrombospondin with Extracellular Matrix Proteins: Selective Binding to Type V Collagen, The Journal of Cell Biology, 1984, vol. 98, pp. 646-652.
Labrou, Design and selection of ligands for affinity chromatography, Journal of Chromatography B, 2003, vol. 790, pp. 67-78.
Dumas et al., Crystal Structure of the Wild-type von Willebrand Facotor A1-Glycoprotien lbα Complex Reveals Conformation Differences with a Complex Bearing von Willebrand Disease Mutations, The Journal of Biological Chemistry, May 28, 2004, vol. 279, pp. 23327-23334.
Zardi et al., Elution of fibronectin proteolytic fragments from a hydroxyapatitie chromatography column, Eur. J. Biochem., 1985, vol. 146, pp. 571-579.
Schroder et al., Hydroxyapatite chromatography: altering the phosphate-dependent elution profile of protein as a function of pH, Analytical Biochemistry, 2003, vol. 313, pp. 176-178.
Daniel Marshak (1996), Cold Spring Harbor Laboratory Press, Strategies for Protein Purification and Characterization: A Laboratory Course Manual, p. 58.
Zykova T A et al., “A Simple and Effective Additional Step in Purification of Bovine Blood Serum Fibronectin”, XP002352960, BIOSIS Database Accession No. PREV19847804777 (1983).
Barington, K. A. et al., “A Very High Purity Von Willebrand Factor Preparation Containing High Molecular Weight Multimers”, Vox Sanguinis, vol. 76, pp. 85-89 (Mar. 1999).
Lethagen, S. et al., “A Comparative In Vitro Evaluation of Six Von Willebrand Factor Concentrates”, Haemophilia, vol. 10, No. 3, pp. 243-249 (May 2004).
Burnouf-Radosevich, M. et al., “Chromatographic Preparation of a Therapeutic Highly Purified Von Willebrand Factor Concentrate from Human Cryoprecipitate”, Vox Sanguinis, vol. 62, No. 1, pp. 1-11 (1992).
Veyradier, A. et al., “Laboratory Diagnosis of Von Willebrand Disease”, vol. 28, No. 4, pp. 201-210 (Dec. 1998).
Federici, Augusto B., “The Factor VIII/von Willebrand Factor Complex: Basic and Clinical Issues”, J. Hematology, vol. 88, suppl. 9, pp. 3-12 (May 2003).
Gorman, J. J. et al., “Studies on the Structure and Subunit Composition of Human Antihaemophilic Factor”, Thrombosis Research, vol. 12, pp. 341-352 (1978).
Saundry, R. H. et al., “Chromatography of vWF on Dextran Sulphate Sepharose”, Thrombosis Research, vol. 48, pp. 641-652 (1987).
Janson, J.C. et al. (editors), “Protein Purification: Principles, High Resolution Methods, and Applications”, Second edition, Wiley-Liss, NY, pp. 190-191, 199-200 (1998).
Bernardi, Giorgio, “Chromatography of Proteins on Hydroxyapatite”, Methods in Enzymology, vol. 27, pp. 471-479 (1973).
Written Opinion of the International Searching Authority issued in PCT/EP05/009728 (PCT/ISA/237).
Kretschmar Michael
Moeller Wolfgang
Biotest AG
Kim Alexander D
Smith Chalin
Smith Patent Consulting LLC
LandOfFree
Production of a von Willebrand factor preparation using... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Production of a von Willebrand factor preparation using..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Production of a von Willebrand factor preparation using... will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-2686800