Production of a deoxyribonucleoside

Details Production of a deoxyribonucleoside Production of a deoxyribonucleoside

1989-05-22

1992-03-03

Wax, Robert A.

Chemistry: molecular biology and microbiology

Micro-organism, tissue cell culture or enzyme using process...

Preparing compound containing saccharide radical

435 84, 435 85, 435 89, 435803, 435840, 536 22, 536 23, 536 29, 536124, 536127, C12P 1938, C12P 1926, C12P 1930, C07H 1512

Patent

active

050932446

ABSTRACT:
A process for the fermentative production of the deoxyribonucleoside thymidine and/or its corresponding base thymine by aerobically cultivating a strain of the genus Brevibacterium, in particular one of the strains NCIMB 40117 and 40116. The produced thymidine may be used as an intermediate in the production of azidothymidine and active ingredient in a composition for use in the treatment of auto imune deficiency syndrome (AIDS). Biologically pure cultures of strain NCIMB 40014 and variants and mutants derived therefrom are claimed per se.

REFERENCES:
patent: 3249511 (1966-05-01), Okumura et al.
patent: 3444040 (1969-05-01), Nara et al.
patent: 3586604 (1971-06-01), Yamanoi et al.
patent: 3912587 (1975-10-01), Enei et al.

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