Production of 7-(2-aminomethylphenylacetamido)-3-(1-carboxymethy

Details Production of 7-(2-aminomethylphenylacetamido)-3-(1-carboxymethy Production of 7-(2-aminomethylphenylacetamido)-3-(1-carboxymethy

1979-07-05

1981-01-06

Rizzo, Nicholas S.

Organic compounds -- part of the class 532-570 series

Organic compounds

Chalcogen in the nitrogen containing substituent

424246, C07D50104

Patent

active

042438039

ABSTRACT:
Ceforanide is produced by the reduction in aqueous solution of a water-soluble salt 7-(2-azido-methylphenylacetamido)-3-(1-carboxymethyltetrazol-5-ylthiomethy l)-3-cephem-4-carboxylic acid using a borane-amine complex and Raney nickel.

REFERENCES:
patent: 2860167 (1958-11-01), Brown
patent: 3035904 (1962-05-01), Brown
patent: 4100346 (1978-07-01), Gottstein et al.
patent: 4118563 (1978-10-01), Lim et al.
Burg et al., JACL 59, 780-787, (1937).
Suzuki, J. Amer. Chem. Soc. 93 4329-4330, (1971).
Lane, Aldrichimica Acta 6(3) 51-58, (1973).

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