Production of 3-chloro-4-fluoro-benzoyl chloride by Lewis-acid c

Details Production of 3-chloro-4-fluoro-benzoyl chloride by Lewis-acid c Production of 3-chloro-4-fluoro-benzoyl chloride by Lewis-acid c

1998-09-10

2000-05-23

Geist, Gary

Organic compounds -- part of the class 532-570 series

Organic compounds

Carboxylic halides

562864, C07C 5158, C07C 5164

Patent

active

060667648

ABSTRACT:
The present invention relates to halogenated aromatic derivatives, in particular 3-chloro-4-fluoro-benzoyl chloride having the following formula: ##STR1## The aforesaid derivative is advantageously used as base product for the preparation of fluorinated compounds employed in their turn as active principles in the pharmaceutical and agricultural fields as well as in dye industry.
The present invention also relates to a process for the preparation of 3-chloro-4-fluoro-benzoyl chloride that allows to obtain the end compound with high selectivity, high yields and one only step starting from a known and commercially available product

REFERENCES:
patent: 4315766 (1982-02-01), Hamprecht et al.
Kirk-Othmer Encyclopedia of Chemical Technology; Wiley-Interscience; vol. 6, pp. 90-92, 1993.
Adams et al. J. Am Chem Soc.; vol. 72; p. 2454, 1950.
Carey, Organic Chemistry; McGraw-Hill; New York; Table 13.1 p 452, 1987.
Weissberger, A.; Ed.; Techniques of Organic Chemistry, vol IV: Distillation; Interscience, New York; table of contents, 1951.

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