Production of 2-(thio substituted)cephalosporin sulfoxides and 2

Details Production of 2-(thio substituted)cephalosporin sulfoxides and 2 Production of 2-(thio substituted)cephalosporin sulfoxides and 2

1973-11-23

1976-07-06

Coughlan, Jr., Paul M.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

424246, C07D50104, C07D50118

Patent

active

039681092

ABSTRACT:
A new method of producing 2-(thio substituted) cephalosporin derivatives comprises treating a cephem sulfoxide with an electrophilic sulfur reagent in the presence of a strong base. The cephem sulfoxides produced by this step are useful as intermediates, which by reduction of the sulfoxide group, yield 2-(thio substituted) cephalosporins having useful antimicrobial activity.

REFERENCES:
patent: 3660395 (1972-05-01), Wright et al.
patent: 3852282 (1974-12-01), Dolfini

Affiliated with

Also associated with

Rating

Production of 2-(thio substituted)cephalosporin sulfoxides and 2 does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Production of 2-(thio substituted)cephalosporin sulfoxides and 2, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Production of 2-(thio substituted)cephalosporin sulfoxides and 2 will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-1532654