Chemistry: molecular biology and microbiology – Process of utilizing an enzyme or micro-organism to destroy... – Resolution of optical isomers or purification of organic...
Patent
1990-10-29
1991-10-29
Weimar, Elizabeth C.
Chemistry: molecular biology and microbiology
Process of utilizing an enzyme or micro-organism to destroy...
Resolution of optical isomers or purification of organic...
435135, 435136, 435874, C07C 7148, C12P 762, C12P 740
Patent
active
050616293
ABSTRACT:
Enantiomerically pure (2R)-2-hydroxy arylalkanoic acid esters and (2S)-2-hydroxy arylalkanoic acids are prepared by the Pseudomonas lipase-catalyzed selective hydrolyxis of racemic (2RS)-2-hydroxy arylalkanoic acid esters in solution or suspension in an aqueous medium at a controlled pH of from about 5 to about 9.
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Coffen David L.
Kalaritis Panayiotis
Patridge John J.
Gould George M.
Hoffman-La Roche Inc.
Kass Alan P.
Leon Bernard S.
Poulos Gail
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