Production of 1-oxacephams and intermediates

Chemistry of carbon compounds – Miscellaneous organic carbon compounds – C-metal

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2602454, 544 90, 560168, 560170, 560174, 560183, 549419, 549420, C07D20508, C07D48704, C07D30912, C07D40312

Patent

active

045391483

ABSTRACT:
Useful intermediates, 7.alpha.-acylamino-3-(oxo or exomethylene)-1-dethia-1-oxacepham-4.alpha.-carboxylates, are produced by the intramolecular carbenoid insertion of a 2-diazo-3-(oxo or exomethylene)-4-(3.alpha.-acylamino-2-oxoazetidin-4.beta.-yl)oxybutyrate prepared in several steps from the corresponding oxazolinoazetidinone and diketone.

REFERENCES:
Shibahara et al., Chem. Abs. 99, 139636z, (1983).

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