Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Preparing oxygen-containing organic compound
Patent
1996-07-26
1998-10-13
Grimes, Eric
Chemistry: molecular biology and microbiology
Micro-organism, tissue cell culture or enzyme using process...
Preparing oxygen-containing organic compound
435232, 4352523, 43525231, 43525233, 43525235, 4352525, 4352527, 4353201, 536 231, 536 232, 536 237, C12P 718
Patent
active
058210920
ABSTRACT:
A process is provided for the bioconversion of glycerol to 1,3-propanediol in which genes from a bacteria known to possess a diol dehydratase enzyme for 1,2-propanediol degradation are cloned into a bacterial host and the host is grown in the presence of glycerol; expression of the foreign genes in the host cell facilitates the enzymatic conversion of glycerol to 1,3-propanediol which is isolated from the culture.
REFERENCES:
patent: 4935554 (1990-06-01), Murphy et al.
patent: 4962027 (1990-10-01), Slininger et al.
patent: 5015789 (1991-05-01), Arntz et al.
patent: 5164309 (1992-11-01), Gottschalk et al.
patent: 5254467 (1993-10-01), Kretschmann et al.
J. Bacteriol. (1995), 177(15), 4392-401, Daniel, Rolf et al., "Biochemical and Molecular Characterization of the Oxidative Branch of Glycerol Utilization by Citrobacter Freundii".
J. Bacteriol., vol. 177, No. 8, 1995, pp. 2151-2156, Daniel, Rolf et al., "Purification of 1,3-Propanediol Dehydrogenase from Citrobacter Freundii and Cloning, Sequencing and Overexpression of the Corresponding Gene in Escherichia Coli".
Gene, vol. 85, 1989, pp. 209-214, Paige E. Goodlove et al., "Cloning and Sequence Analysis of the Fermentative Alcohol-Dehydrogenase-Encoding Gene of Escherichia Coli".
Daniel et al, FEMS Microbiol. Lett., 100, 281-286 (1992).
Forage, R.G. et al, Bacteriology, 149(2), 413-419 (1982).
Jeter, R.M., J. Gen. Microbiology, 136, 887-896 (1990).
Tong, I-T et al, Appl. and Environmental Microbiology, 57(12), 3541-3546 (1991).
Ichikawa et al, J. Ferment. Technol., 63(2), 135-141 (1985).
Sprenger, G.A. et al, J. Gen. Microbiology, 135, 1255-1262 (1989).
Boenigk, R. et al, Appl. Microbiol. and Biotechnol., 38, 453-457 (1993).
Forsberg, C.W., Appl. Environ. Microbiol., 53(4), 639-643 (1987).
Zeng, A-P. et al, Enzyme Microb. Technol., 15, 770-779 (1993).
Bobik, T.A. et al, J. of Bacteriol., 174(7), 2253-2266 (1992).
Hartmanis, M.G.N. et al, Archives of Biochem. and Biophysics, 245(1), 144-152 (1986).
Tobimatsu, T. et al, J. Biol. Chem., 270(13), 7142-7148 (1995).
Tong et al. "1,3-Propanediol production by Escherichia coli expressing genes from the Klebsiella pneumoniae dha regulon" App. Envirn. Microbiol. 57, 3541-3546 Dec. 1991.
Daniel et al. "Growth temperature-dependent activity of glycerol dehydratase in . . . " FEMS Microbiol. Lett. 100, 281-286 Dec. 1992.
Tobimatsu et al. "Molecular cloning, sequencing, and expression of the genes encoding . . . " J. Biol. Chem. 270, 7142-7148 Mar. 1995.
McGee et al. "Diol dehydrtase: N-terminal amino acid sequence and subunit stochiometry" Biochem. Biophys. Res. Comm. 108, 547-551 Sep. 1982.
Nagarajan Vasantha
Nakamura Charles Edwin
E. I. Du Pont de Nemours and Company
Grimes Eric
Nashed Nashaat T.
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