Production methods of citalopram and intermediates therefor

Organic compounds -- part of the class 532-570 series – Organic compounds – Oxygen containing

Reexamination Certificate

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Reexamination Certificate

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06930211

ABSTRACT:
The present invention provides a production method of a compound of the formulawherein X is chlorine atom, bromine atom or iodine atom, as well as a production method of citalopram and intermediates therefor.

REFERENCES:
patent: 3642997 (1972-02-01), Shen et al.
patent: 3835167 (1974-09-01), Pfister
patent: 4136193 (1979-01-01), Bøgesøet al.
patent: 4898864 (1990-02-01), Maignan et al.
patent: 5061810 (1991-10-01), Ramachandran
patent: 6291689 (2001-09-01), Petersen et al.
patent: 6310222 (2001-10-01), Ikemoto et al.
patent: 6395910 (2002-05-01), Ikemoto et al.
patent: 6420574 (2002-07-01), Petersen et al.
patent: 6433195 (2002-08-01), Ikemoto et al.
patent: 6433196 (2002-08-01), Ikemoto et al.
patent: 6458975 (2002-10-01), Ikemoto et al.
patent: 2001/0027256 (2001-10-01), Petersen et al.
patent: 2002/0004604 (2002-01-01), Petersen et al.
patent: 2002/0095051 (2002-07-01), Ikemoto et al.
patent: 2002/0151728 (2002-10-01), Ikemoto et al.
patent: 2003/0060640 (2003-03-01), Petersen
patent: 2003/0083508 (2003-05-01), Petersen et al.
patent: 2003/0109577 (2003-06-01), Liljegren et al.
patent: 2003/0114692 (2003-06-01), Petersen et al.
patent: 2003/0134895 (2003-07-01), Petersen et al.
patent: 26 57 013 (1977-07-01), None
patent: 0 178 184 (1986-04-01), None
patent: 04-210687 (1992-07-01), None
patent: WO 93/14055 (1993-07-01), None
patent: WO 98/19511 (1998-05-01), None
patent: WO 99/30548 (1999-06-01), None
patent: WO 00/26167 (2000-05-01), None
patent: WO 01/68632 (2001-09-01), None
patent: WO 01/85712 (2001-11-01), None
Allinger, “Organic Chemistry,” pp. 452-455 (1971).
Beilstein, EIII/IV 18, Syst. Nr. 2619/H418 (1951).
Bigler et al., “Quantitative Structure-Activity Relationships in a Series of Selective 5-HT Uptake Inhibitors,”European Journal of Medicinal Chemistry, Editions Scientifique Elsevier, 12(3), 289-295 (XP-000944915) (1977).
Carruthers, W., “Some Modern Methods of Organic Synthesis,” 3rdEdition,Chemistry Department—University of Exeter,Cambridge University Press, Cambridge, Great Britain, pp. 457-478 (1986).
Constantinides et al., “Reactions of Molecules with Two Equivalent Functional Groups. 2. Acetylation of the Isomers of Bis(Hydroxymethyl)benzene,” Journal of Physical Organic Chemistry, 3 (12), 789-798 (1990).
Dokunikhin et al., “Anthraquinone Derivatives. III. Synthesis of Fluoro-substituted 2-Anthraquinone-Carboxylic Acid and 2-Aminoanthraquinone,”Chemical Abstracts, 60(13), 537b (1964).
Goethals et al., “Basicity of Benzophenones and Polysubstituted 2-Methylbenzophenones. Role of Molecular Twisting and Electronic Interactions in the Transmission of Substituent Effects,”Chemical Abstracts Service,Database Accession No. 83:178083 (1975).
Gómez et al., “DTBB-Catalysed Lithiation of Chlorinated Benzylic Chlorides, Alcohols, Thiols or Amines,”Tetrahedron, 54(9), 1853-1866 (1998).
Huntress et al., “4-Nitrophthalimide,” Organic Synthesis II, p. 459 (1943).
Kirmse et al., “Carbenes and the O—H Bond: Hydroxyalkyl-Substituted Arylcarbenes,”J. Org. Chem., 55(8), 2325-2332 (1990).
Levy et al., “4-Aminophthalide and Some Derivatives,” Journal of Chemical Society, p. 867 (1931).
“Phthalides Substituted at 5,” Bull. Soc. Sci. Bretagne, Chapter II: 35-43 (1951).
Rigaudy et al., “Transformations Thermiques des PhotoxydesMesodes Acenes-IV,”Tetrahedron,The International Journal for the Rapid Publication of Critical Reviews and Original Research Communications in Organic Chemistry, Pergamon Press, Oxford, Great Britain, 34, 113-121 (1978).
Verbeerst et al., “Friedel-Crafts Acylation. V. Polar and Steric Substituent Effects in the Reaction of Disubstituted Benzoyl Chlorides Carrying a Constant Ortho-Substituent,”Chemical Abstracts Service,Database Accession No. 70:2962 (1969).

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