Liquid purification or separation – Processes – Chromatography
Patent
1992-08-18
1993-06-29
Dawson, Robert A.
Liquid purification or separation
Processes
Chromatography
73 6158, 2101982, 422 70, 356128, 356136, B01D 1508
Patent
active
052231429
ABSTRACT:
A critical angle refractive index detector for production liquid chromatography systems with flow rates as low as 100 ml/min to 25 l/min or higher as the system requires and pressures up to 4000 psi. The detector includes a flow cell with a sensing chamber volume selected to provide maximum detector sensitivity and minimum pressure drop at the maximum flow rate of the system for accurate discernment of critical refractive index peaks of each constituent in the sample. Explosion protected controls for zero and span settings are located to the exterior of a purged safe enclosure containing the system.
REFERENCES:
patent: 2807976 (1957-10-01), Vossberg
patent: 3628867 (1971-12-01), Brady
patent: 3999856 (1976-12-01), Unterleitner
patent: 3999857 (1976-12-01), David et al.
patent: 4952055 (1990-08-01), Wyatt
L. R. Snyder & J. J. Kirkland, "Introduction to Modern Liquid Chromatography", John Wiley & Sons, Inc., New York (1979) pp. 123, 129-130, 636-639.
Z. Deyl, K. Macek, & J. Janak, "Liquid Column Chromatography", Elsevier, Amsterdam (1975), pp. 146-149, 151-153.
Biotage Inc.
Dawson Robert A.
Kim Sun Uk
Parker Sheldon H.
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