Drug – bio-affecting and body treating compositions – Immunoglobulin – antiserum – antibody – or antibody fragment,... – Structurally-modified antibody – immunoglobulin – or fragment...
Reexamination Certificate
2005-11-08
2005-11-08
Saunders, David (Department: 1644)
Drug, bio-affecting and body treating compositions
Immunoglobulin, antiserum, antibody, or antibody fragment,...
Structurally-modified antibody, immunoglobulin, or fragment...
C424S001530, C424S009340, C424S094610, C424S133100, C424S155100, C424S156100, C424S179100, C424S181100, C424S183100
Reexamination Certificate
active
06962702
ABSTRACT:
The present invention relates to a bi-specific antibody or antibody fragment having at least one arm that is reactive against a targeted tissue and at least one other arm that is reactive against a linker moiety. The linker moiety encompasses a hapten to which antibodies have been prepared. The antigenic linker is conjugated to one or more therapeutic or diagnostic agents or enzymes. The invention provides constructs and methods for producing the bispecific antibodies or antibody fragments, as well as methods for using them.
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patent: 5683694 (1997-11-01), Bagshawe et al.
patent: 6096289 (2000-08-01), Goldenberg
patent: 9966951 (1999-12-01), None
Griffiths Gary L.
Hansen Hans J.
Leung Shui-on
McBride William J.
Qu Zhengxing
Heller Ehrman LLP
Immunomedics Inc.
Saunders David
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