Production and use of isolated type 5 17.beta.-hydroxysteroid de

Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Recombinant dna technique included in method of making a...

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4353201, 435325, 536 232, C12N 510, C12N 1509, C12N 1512, C12N 1563

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active

061241156

ABSTRACT:
A novel type 5 17.beta.-hydroxysteroid dehydrogenase is provided. Methods of producing the enzyme and using the enzyme to identify potential compounds which inhibit or alter the activity of the enzyme are described. In addition, methods of using the gene sequence or portions thereof for probes or to produce expression-disrupting sense or antisense DNA fragments thereof, or antisense RNA, are provided.

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