Production and diagnostic use of antibodies against pancreatic a

Chemistry: molecular biology and microbiology – Spore forming or isolating process

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4351722, 530387, 530845, 935104, C12N 500, C12N 1500

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active

049525077

ABSTRACT:
Antibodies specific for pancreatic alpha-amylase and methods for their production are described. These antibodies may be used for the detection and quantification of pancreatic alpha-amylase in biological fluids, tissue extracts, or extracts of stains of biological fluids.

REFERENCES:
Urdal et al., "Macroamylase Immunoglobulins Show High Affinity for Animal and Human Amylases", Clinical Chemistry 31:699-703 (May 1985).
Hiroishi et al., "Differential Assay of Human Salivary and Pancreatic .alpha.-Amylase Using a Monoclonal Antibody Insolubilized on Bacterial Cell Wall", Clinica Chimica Acta 159:89-91 (Aug. 1986).
Gerber et al., "Inhibition of Human Saliva and Pancreas Amylase by Monoclonol Antibodies", Chemical Abstracts 106: #29347m, Eur. Pat. Appl. EP 194,600, 17 Sep. 1986, DE Appl. 3,508,384, 08 Mar. 1985 (2 Feb. 1987).
Bruns et al., Clin. Chem. 31(8):12867-1288 (1985).
M. Gerber et al., Clin. Chem. 32(6):1131 (1986).
T. E. Mifflin et al., Clin. Chem 31(8):1283-1286 (1985).
M. Gerber et al., Clin. Chem. 31(8):1331-1334 (1985).
K. Ito et al., J. Biochem. 97:1357-1362 (1985).

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