Product and process to regulate actin polymerization

Details Product and process to regulate actin polymerization Product and process to regulate actin polymerization

1995-09-27

1998-12-22

Leary, Louise

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving viable micro-organism

435 23, 435 21, 435 651, 435 691, 435 692, 435 17, 435 4, 435975, 435968, 435 71, 435 72, 435 721, 435 723, 435 724, 4242781, 424 941, 424 945, C12Q 102, C12Q 137, C12Q 100, G01N 3353

Patent

active

058517863

ABSTRACT:
The present invention relates to methods useful for identifying compounds capable of specifically regulating actin polymerization, stress fiber formation or focal adhesion assembly by regulating G.sub..alpha.12 and/or G.sub..alpha.13 activity in cells involved in inflammatory responses, immune responses, allergic responses and neuronal responses, kits to perform such assays and methods to control disease related to such responses.

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