Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues – Blood proteins or globulins – e.g. – proteoglycans – platelet...
Patent
1994-09-19
1997-12-16
Feisee, Lila
Chemistry: natural resins or derivatives; peptides or proteins;
Proteins, i.e., more than 100 amino acid residues
Blood proteins or globulins, e.g., proteoglycans, platelet...
4241301, 4241331, 4241341, C12P 2108, A61K 39395, A61K 3940, A61K 3942
Patent
active
056986793
ABSTRACT:
The present invention relates to a product and process for regulating an immune system using an immunoglobulin fusion protein capable of targeting a specific peptide precursor to a specific antigen presenting cell. Disclosed is a peptide precursor associated with an immunoglobulin molecule capable of binding to an antigen on the surface of an antigen presenting cell. Also disclosed is a nucleic acid molecule having a sequence encoding an immunoglobulin fusion protein comprising a peptide precursor and an immunoglobulin molecule. The invention is additionally directed to therapeutic reagents which can act as toleragens or immunogens useful in the regulation of an immune response.
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Eyler Yvonne
Feisee Lila
National Jewish Center for Immunology and Respiratory Medicine
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