Producing a high content of acetate kinase using bacillus stearo

Details Producing a high content of acetate kinase using bacillus stearo Producing a high content of acetate kinase using bacillus stearo

1995-06-02

1997-03-11

Wityshyn, Michael G.

Chemistry: molecular biology and microbiology

Enzyme , proenzyme; compositions thereof; process for...

Transferase other than ribonuclease

4352521, 4352525, C21N 912, C21N 120

Patent

active

056100450

ABSTRACT:
A process is described for cultivating thermophilic bacteria of the genus Bacillus having the ability to produce acetate kinase, wherein said cultivation is carried out continuously at a dilution rate (D) in the range from about 0.9 .mu..sub.max to 1.0 .mu..sub.max, wherein D is the dilution rate (1/hr), and .mu..sub.max is the maximum specific growth rate (1/hr), to thereby produce bacterial cells having a high content of acetate kinase.

REFERENCES:
Purification and Properties of Acetate Kinase from Bacillus Stearothermophilus, J. Biochem, vol. 84, 1978, pp. 193-203, Nakajima et al.
Industrial Applications of Microbiology, John Wiley & Sons 1977 pp. 72-77.

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