Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1989-02-01
1990-07-24
Chan, Nicky
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
514 25, 536 41, 549375, 549229, A61K 31335, A61K 3170, C07D31906, C07H 1526
Patent
active
049435884
ABSTRACT:
Prodrugs of 3-hydroxy-3-methylglutarylcoenzyme A (HMG-CoA) reductase inhibitors which are useful as antihypercholesterolemic agents and are represented by the following general structural formula (I): ##STR1## are disclosed.
REFERENCES:
patent: 4584389 (1986-04-01), Sletzinger et al.
Hirama et al., JACS, 104, 4251, (1982).
Suntry, C.A., 100, 156,496k, (1984).
Halczenko Wasyl
Hartman George
Pitzenberger Steven M.
Chan Nicky
DiPrima Joseph F.
Merck & Co. , Inc.
Winokur Melvin
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