Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Reexamination Certificate
2005-05-31
2005-05-31
Owens, Amelia A. (Department: 1625)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
C514S339000, C546S270100
Reexamination Certificate
active
06900229
ABSTRACT:
The present invention relates to new compounds of general formulahaving thrombin-inhibiting activity. Exemplary are:1-Methyl-2-[4-(N-hydroxyamidino)-phenylaminomethyl]-benzimidazol-5-yl-carboxylic acid-(N-2-pyridyl-N-2-ethoxycarbonylethyl)-amide, and1-Methyl-2-[4-(N-methoxycarbonylamidino)-phenylaminomethyl]-benzimidazol-5-yl-carboxylic acid-(N-2-pyridyl-N-2-hydroxycarbonylethyl)-amide.
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patent: 6469039 (2002-10-01), Hauel et al.
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patent: WO 98/37075 (1998-08-01), None
Hauel, N. et al; “Disubstituted Bicyclic Heterocycles, The Preparation Thereof And Their Use As Pharmaceutical Compositions”; USSN 10/192,041, filed Jul. 10, 2002.
Busch Ulrich
Colbatzky Florian
Hauel Norbert
Blankinship Thomas
Boehringer Ingelheim Pharma GmbH & Co. KG
Devlin Mary-Ellen M.
Morris Michael P.
Owens Amelia A.
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