Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Sulfur – selenium or tellurium compound
Reexamination Certificate
2011-04-26
2011-04-26
Kosack, Joseph R (Department: 1626)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Sulfur, selenium or tellurium compound
C568S022000
Reexamination Certificate
active
07932294
ABSTRACT:
The invention provides the compounds of formula (I) or pharmaceutically acceptable salts thereof. The invention also provides pharmaceutical compositions comprising one or more compounds of formula I or intermediates thereof and one more of pharmaceutically acceptable carriers, vehicles or diluents. The invention further provides methods of preparation and methods of use of prodrugs including NO-releasing prodrugs, double prodrugs and mutual prodrugs comprising the compounds of formula I.
REFERENCES:
patent: 5767134 (1998-06-01), Li et al.
patent: 5807847 (1998-09-01), Thatcher et al.
patent: 5883122 (1999-03-01), Thatcher et al.
patent: 6369071 (2002-04-01), Haj-Yehia
patent: 6566509 (2003-05-01), Griffin et al.
patent: 2003/0044845 (2003-03-01), Jenkins et al.
patent: 2004/0147598 (2004-07-01), Haj-Yehia
patent: 2005/0002942 (2005-01-01), Vlahov et al.
patent: 0317956 (1989-05-01), None
patent: WO97/46521 (1997-12-01), None
patent: WO98/42661 (1998-10-01), None
patent: WO99/58152 (1999-11-01), None
patent: WO00/54756 (2000-09-01), None
patent: WO0064483 (2000-11-01), None
patent: WO 01/13957 (2001-03-01), None
patent: WO01/49275 (2001-07-01), None
patent: WO03/000643 (2003-01-01), None
patent: WO 03/040104 (2003-05-01), None
patent: WO2004/004648 (2004-01-01), None
patent: WO2004/012659 (2004-02-01), None
patent: WO 2004/039771 (2004-05-01), None
patent: WO 2004/069159 (2004-08-01), None
patent: WO2004/110432 (2004-12-01), None
patent: WO2005/030135 (2005-04-01), None
Smith et al. “Urethans of 2-Mercaptoethanol” Journal of the American Chemical Society, 1959, vol. 81, pp. 161-163.
“Nitric Oxide Donors and Cardiovascular Agents Modulating the Bioactivity of Nitric Oxide: An Overiew” by Louis J. Ignarro, et al.,Circulation Research, vol. 90, No. 1, pp. 21-28 (Jan. 11, 2002).
“Bis[3-(4′-substituted phenyl) prop-2-ene]disulfides as a new class of antihyperlipidemic compounds” by Meenakshi Sharma, et al.,Bioorganic and Medicinal Chemistry Letters, vol. 14, No. 21, pp. 5347-5350 (Nov. 1, 2004).
Abstract Only “Spectrophotometric determination of binary mixtures of pseudoephedrine with some histamine H1-receptor antagonists using derivative ratio spectrum method” by H. Mahgoub, et al.,J. Pham Biomed Anal, vol. 31, No. 4, pp. 801-809 (Mar. 26, 2003).
Abstract, Guetschow, Michael, et al. DD 293807 (Ger.(East)) (1991).
Abstract, Oiry, J. et al. European Journal of Medicinal Chemistry (1992), 27(8), 809-17.
Abstract, Thoene, Jess G., et al. WO 9306832.
Abstract, Zhdanovich, E.S., et al. Zhurnal Obshchei Khimii (1967), 37(2), 361-3.
Abstract, Oiry, Joel, et al. “Centre National de la Recherche Scientifique, Fr.” Fr. Demande (1983) (FR 2528042).
Abstract, Joel, et al. “Centre National de la Recherche Scientifique, Fr” Eur. Patent Appln. 131500 (1885) 64 pp.
Abstract, Barcelo, Gerard, et al. (Soceite Nationale des Pourdes et Explosifs, Fr. Fr. Demande (1987), FR 2589860.
Abstract, Davidovich, Yu, et al. Izvestiya Akademii Nauk SSSR, Seriya Khimicheskaya (1989), (8), 1918-20.
Abstract, Vecsei, Laszlo, et al. Progress in Neuro-Psychopharmacology & Biological Psychiatry (1990), 14(6), 835-62.
Abstract, Thoene, Jess G., et al. WO 9306832, 1993.
Peter D. Senter et al., Development of Drug-Release Strategy Based on the Reductive Fragmentation pf Benzyl Carbamate Disulfides. Journal of Organic Chemistry, 1990, 55, 2975-2978. Published by American Chemical Society (USA).
Vivekananda M. Vrudhula et al., Reductively Activated Disulfide Prodrugs of Paclitaxel. Biorganic & Medicinal Chemistry Letters, 2002, 12, 3591-35-94, Published by Elsvier Sciences Ltd. (USA).
Samuel Zalipsky et al., New Detachable Poly(ethylene glycol) Conjugates: Cysteine-cleavable Lipopolymers Regenerating Natural Phospholipid, Diacyl Phosphatidylethanolamine. Bioconjugate Chemistry, Published by American Chemical Society (USA), 1999, vol. 10, No. 5, pp. 703-707.
Kexin Yang et al., Synthesis of novel organic nitrate esters: guanylate cyclase activation and tissue relaxation. Journal of Chemical Society, Perkin Transitions 1, 1996, 1073-1075, Publised by Royal Society of Chemistry (UK).
Sergei I. Zavorin et al., Nitrate Esters as Nitric Oxide Donors: SS-Nitrates. Organic Letters, 2001, 3 (8), 1113-1116. Published by American Chemical Society (USA).
Apparao Satyam
Kosack Joseph R
Ladas & Parry LLP
Piramal Life Sciences Limited
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