Prodrug esters of phenolic 2-piperidino-1-alkanols

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...

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514316, 514326, 544129, 546190, 546208, 546216, 546217, A61K 31535, C07D41312, C07D40112, C07D21154

Patent

active

056543026

ABSTRACT:
Phenolic prodrug esters of certain 1-(hydroxyphenyl)-2-piperidino-1-alkanol derivatives, which are useful in the treatment of stroke, traumatic head injury and CNS degenerative disease; and intermediates useful in their synthesis.

REFERENCES:
patent: 5185343 (1993-02-01), Chenard
patent: 5272160 (1993-12-01), Chenard
patent: 5338754 (1994-08-01), Chenard
patent: 5391742 (1995-02-01), Chenard
Bundagard et al, J. Med Chem., 32, 2503-07 (1989).

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