Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues – Scleroproteins – e.g. – fibroin – elastin – silk – etc.
Patent
1997-01-10
1998-12-29
Tsang, Cecilia J.
Chemistry: natural resins or derivatives; peptides or proteins;
Proteins, i.e., more than 100 amino acid residues
Scleroproteins, e.g., fibroin, elastin, silk, etc.
20415715, 2041576, 20415768, 514 21, A61K 3817, C08K 300
Patent
active
058543970
ABSTRACT:
The present invention relates to a process for cross-linking a proteinaceous material. The process comprises: i) soaking the material to be cross-linked in an agueous solution of high osmolality; ii) incubating the material in an agueous buffer including an amount of a photooxidative catalyst sufficient to catalyze photooxidation of the material; and iii) irradiating the material and the catalyst of step (i) with light that includes a range of wavelengths selectively absorbed by the catalyst. Irradiation is effected under conditions such that cross-linking of the material occurs. In a further embodiment, the present invention relates to a cross-linked product produced by the above-described method.
REFERENCES:
patent: 3152976 (1964-10-01), Kuntz
patent: 5024742 (1991-06-01), Nesburn et al.
patent: 5147514 (1992-09-01), Mechanic
patent: 5332475 (1994-07-01), Mechanic
Vater et al, Biochem. J., vol. 181, No. 3, pp. 639-645, 1979.
Barher et al. Biochem. Biophy. Acta, vol. 632, No. 4, pp. 589-597, 1980.
Carpentier et al, J. Thorac. Cardiovasc. Surg., vol. 62, No. 5, pp. 707-713, 1971.
Collins et al Biochem. Biophys. Acta, vol. 493, No. 1, pp. 129-139, 1977.
Mannschott et al, Biochem. Biophys. Acta, vol. 434, No. 1, pp. 177-183, 1976.
Barrow Kenneth S.
Mohamed Abdel A.
Tsang Cecilia J.
University of North Carolina at Chapel Hill
Wisner Mark R.
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