Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...
Reexamination Certificate
2005-08-23
2005-08-23
Trinh, Ba K. (Department: 1625)
Organic compounds -- part of the class 532-570 series
Organic compounds
Heterocyclic carbon compounds containing a hetero ring...
C549S297000
Reexamination Certificate
active
06933395
ABSTRACT:
Process for the production of drospirenone (6β,7β; 15β,16β-dimethylene-3-oxo-17α-pregn-4-ene-21,17-carbolactone, DRSP) (1) and 7α-(3-hydroxy-1-propyl)-6β,7β; 15β,16β-dimethylene-5β-androstane-3β,5,17β-triol (ZK 92836) and 6β,7β; 15β,16β-dimethylene-5β-hydroxy-3-oxo-17α-androstane-21,17-carbolactone (ZK 90965) as intermediate products of the process.
REFERENCES:
patent: 4129564 (1978-12-01), Wiechert et al.
patent: 4416985 (1983-11-01), Petzoldt et al.
patent: 4435327 (1984-03-01), Petzoldt et al.
patent: 4614616 (1986-09-01), Petzoldt et al.
patent: 4904462 (1990-02-01), Schulze et al.
patent: 5106995 (1992-04-01), Plotkin
patent: 2652761 (1978-05-01), None
patent: 30 22 337 (1982-07-01), None
patent: 3626838 (1988-02-01), None
patent: 0051143 (1982-05-01), None
patent: 0075189 (1983-03-01), None
patent: WO 90/14344 (1990-11-01), None
patent: 9014344 (1990-11-01), None
Bittler et al., “Synthesis of Spirorenone-A Novel Highly Active Aldosterone Antagonist,”Angewandte Chemie. International Edition, vol. 21, Issue 9, pp. 696-697 (1982).
Nickisch K et al., “Acid catalyzed rearrangements of 15-beta 16-beta methylene-17-alpha-pregnene-21 17-carbolactone derivatives,” Tetrahedron Letters, 1986, pp. 5463-5466, vol. 27, No. 45, XP002298941, ISSN: 0040-4039; p. 5463, abstract 2-p. 5464, abstract 1.
Bittler D et al., “Synthesis of spirorenone—a novel highly active aldosterone antagonist,” Angewandte Chemie. International Edition, Verlag Chemie. Weinheim, DE, 1982, pp. 696-697, vol. 21, No. 9, XP002047531, ISSN: 0570-0833; p. 696, split 2, illustration 1.
Mohr Jörg-Thorsten
Nickisch Klaus
Millen White Zelano & Branigan P.C.
Schering AG
Trinh Ba K.
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