PROCESSING FOR PRODUCING OF DROSPIRENONE (6β,...

Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...

Reexamination Certificate

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

C549S297000

Reexamination Certificate

active

06933395

ABSTRACT:
Process for the production of drospirenone (6β,7β; 15β,16β-dimethylene-3-oxo-17α-pregn-4-ene-21,17-carbolactone, DRSP) (1) and 7α-(3-hydroxy-1-propyl)-6β,7β; 15β,16β-dimethylene-5β-androstane-3β,5,17β-triol (ZK 92836) and 6β,7β; 15β,16β-dimethylene-5β-hydroxy-3-oxo-17α-androstane-21,17-carbolactone (ZK 90965) as intermediate products of the process.

REFERENCES:
patent: 4129564 (1978-12-01), Wiechert et al.
patent: 4416985 (1983-11-01), Petzoldt et al.
patent: 4435327 (1984-03-01), Petzoldt et al.
patent: 4614616 (1986-09-01), Petzoldt et al.
patent: 4904462 (1990-02-01), Schulze et al.
patent: 5106995 (1992-04-01), Plotkin
patent: 2652761 (1978-05-01), None
patent: 30 22 337 (1982-07-01), None
patent: 3626838 (1988-02-01), None
patent: 0051143 (1982-05-01), None
patent: 0075189 (1983-03-01), None
patent: WO 90/14344 (1990-11-01), None
patent: 9014344 (1990-11-01), None
Bittler et al., “Synthesis of Spirorenone-A Novel Highly Active Aldosterone Antagonist,”Angewandte Chemie. International Edition, vol. 21, Issue 9, pp. 696-697 (1982).
Nickisch K et al., “Acid catalyzed rearrangements of 15-beta 16-beta methylene-17-alpha-pregnene-21 17-carbolactone derivatives,” Tetrahedron Letters, 1986, pp. 5463-5466, vol. 27, No. 45, XP002298941, ISSN: 0040-4039; p. 5463, abstract 2-p. 5464, abstract 1.
Bittler D et al., “Synthesis of spirorenone—a novel highly active aldosterone antagonist,” Angewandte Chemie. International Edition, Verlag Chemie. Weinheim, DE, 1982, pp. 696-697, vol. 21, No. 9, XP002047531, ISSN: 0570-0833; p. 696, split 2, illustration 1.

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

PROCESSING FOR PRODUCING OF DROSPIRENONE (6β,... does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with PROCESSING FOR PRODUCING OF DROSPIRENONE (6β,..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and PROCESSING FOR PRODUCING OF DROSPIRENONE (6β,... will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-3462876

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.