Processes, reagents and means for early diagnosis of pregnancy

Details Processes, reagents and means for early diagnosis of pregnancy Processes, reagents and means for early diagnosis of pregnancy

1976-06-29

1978-01-31

Scovronek, Joseph

Chemistry: physical processes

Physical processes

Crystallization

424 12, G01N 3316, A61K 3738

Patent

active

040713148

ABSTRACT:
A reagent for the early diagnosis of pregnancy comprising a substrate of suitable erythrocytes or polymer having adsorbed thereon a predetermined ratio of chorionic gonadotropin antigen and antisera therefor. The ratio is selected so as to be insensitive to the presence of less than 1,500 I.U. per liter of chorionic gonadotropin in the urine being tested. The reagent is used by combining with a predetermined quantity of the urine to be tested and after 1/2-2 hours inspecting for agglutination, the presence of which indicates a negative result. An apparatus is also disclosed for carrying out the process.

REFERENCES:
patent: 3234096 (1966-02-01), Pollack
patent: 3309275 (1967-03-01), Treacy
patent: 3579306 (1971-05-01), Crane
Gradwohl, "Clinical Laboratory Methods and Diagnosis," C. V. Mosby Co., St. Louis, 1970, pp. 1576, 1577, 1579-1584.
Todd-Sanford, "Clinical Diagnosis by Laboratory Methods," 14 ed., W. B. Saunders Co., Philadelphia, Pa., 1969, pp. 1181-1187.
Kerber, et al., "Immunologic Tests for Pregnancy," Obstetrics and Gynecology, vol. 36, No. 1, July 1970.

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