Processes of preparing .alpha.-amylase inhibiting subtances from

Details Processes of preparing .alpha.-amylase inhibiting subtances from Processes of preparing .alpha.-amylase inhibiting subtances from

1989-12-06

1992-01-28

Dees, Jose G.

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Conjugate or complex

530375, A61K 3578

Patent

active

050842757

ABSTRACT:
A process of preparing an .alpha.-amylase inhibiting substance from wheat is disclosed which comprises heat treating a supernatant fraction of an aqueous extract of wheat or wheat flour to modify unnecessary protein contaminants in the supernatant fraction, removing a modified protein from said fraction, and subjecting a resulting aqueous solution containing an .alpha.-amylase inhibiting substance to a concentration treatment using an ultrafiltration membrane. As the ultrafiltration membrane is used the membrane of polyacrylonitrile, polyolefin, polysulfone, polyimide or polypropylene materials, each having a fractionation molecular weight of 5,000, 6,000, 8,000, 10,000, 13,000, 20,000, 30,000, 50,000, 100,000 and 200,000 Dalton cut off.

REFERENCES:
patent: 4806626 (1989-02-01), Maeda et al.
patent: 4859468 (1989-08-01), Kubo et al.
patent: 4931278 (1990-06-01), Blost et al.
Biological Abstracts, vol. 77, No. 4, (1984), abstract No. 30591, (Weselake et al.).

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