Processes for the preparation of glyoxal-2-oxims

Details Processes for the preparation of glyoxal-2-oxims Processes for the preparation of glyoxal-2-oxims

1979-08-20

1981-01-06

Sutto, Anton H.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

C07D26112

Patent

active

042438128

ABSTRACT:
Novel derivatives of glyoxal-2-oxim represented by the chemical formula ##STR1## wherein R is hydrogen or a lower alkyl or phenyl group, are provided in accordance with the present invention. These derivatives are prepared by reacting the corresponding isoxazole-5-carbaldehyde with nitromethane in the presence of a metal alkoxide, or the corresponding 5-acetylisoxazole with a nitrate. They have anti-inflammatory and/or analgesic activities.

REFERENCES:
Hartang et al., "Organic Syntheses," Collective vol. 2, (1943), pp. 363-364.

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